The Flying Dutch are 13th out of 22 teams heading into Wednesday's second round of the 72-hole, four-day tournament at Bay Oaks Country Club.
Hope, the Michigan Intercollegiate Athletic Association regular-season and tournament champions, shot a first-round team score of 332.
All five Flying Dutch golfers finished within three strokes of each other.
Molinaro, a senior from Burtchville, Michigan (Port Huron Northern), and Wierenga, a senior from Byron Center, Michigan (South Christian) are tied for 52nd among 116 golfers.
Junior Nicole Meyer of Brighton, Michigan (Brighton) chipped in an 83 and is tied for 59th.
Rhodes, Tennessee is in first place with a score of 301.
This is Hope's third consecutive appearance at the national tournament. The Flying Dutch finished a program-best 10th last season.